HRID13387

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID123350

4-(Methylsulfonyl)phenol

C7H8O3S

结构：CC(=O)OC1CCN(C(C)=O)C1c1cc([N+](=O)[O-])c(NC(=O)c2ccccn2)cc1F

HCID67483074

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OC1CCN(C(C)=O)C1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(S(C)(=O)=O)cc1

HCID67482257

未命名化合物

PROCEDURE

实验过程

The entitled compound was obtained as a white solid in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using 4-(methanesulfonyl)phenol and (1-acetyl-2-(2-fluoro-5-nitro-4-((pyridin-2-ylcarbonyl)amino)phenyl)pyrrolidin-3-yl acetate diastereomer A.

WORKUP

后处理

customThe entitled compound was obtained as a white solid in the same method as in Example 338 (step 5) or in accordance with the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-07de9e32f5b2442db95aef7c86370ae0
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07728025B2
来源说明: uspto-grants-2010_06

反应 SMILES

[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[C:12]([O:15][CH:16]1[CH2:20][CH2:19][N:18]([C:21](=[O:23])[CH3:22])[CH:17]1[C:24]1[CH:29]=[C:28]([N+:30]([O-])=O)[C:27]([NH:33][C:34]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][N:37]=2)=O)=[CH:26][C:25]=1F)(=[O:14])[CH3:13]>>[C:12]([O:15][CH:16]1[CH2:20][CH2:19][N:18]([C:21](=[O:23])[CH3:22])[CH:17]1[C:24]1[C:25]([O:11][C:8]2[CH:9]=[CH:10][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:6][CH:7]=2)=[CH:26][C:27]2[N:33]=[C:34]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][N:37]=3)[NH:30][C:28]=2[CH:29]=1)(=[O:14])[CH3:13]