化工社化工社 化学情報印刷レポート · 研究参考用
N-(tert-butoxycarbonyl)glycine → N-(2-(2-(6-(4-Methanesulfonyl-phenoxy)-2-pyridin-2-yl-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-2-oxo-ethyl)-methanesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(tert-butoxycarbonyl)glycine | HCID 78288 | — |
| 反応物 | 5-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-6-pyrrolidin-2-yl-1H-benzimidazole | HCID 23145175 | — |
| 生成物 | N-(2-(2-(6-(4-Methanesulfonyl-phenoxy)-2-pyridin-2-yl-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-2-oxo-ethyl)-methanesulfonamide | HCID 23145250 | — |
反応手順
The entitled compound was obtained in the same method as in Example 171 and 178 or in accordance with the method or by combining it with an ordinary method but using 5-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-6-pyrrolidin-2-yl-1H-benzimidazole obtained in Example 162 (step 7) and N-t-butoxycarbonyl-glycine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728025B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-a4bd50c417f84796980d10fce0e3b876 |
| 出典メモ | uspto-grants-2010_06 |