HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1339023Generated: November 3, 2026
3-Bromopyridine → 4-(4-Phenylpiperidin-1-yl)pyridine
https://huagongshe.com/reaction/1339023
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | Sodium t-butoxide | HCID 23676156 | — |
| Catalyst | 2-(Dicyclohexylphosphino)-2'-methylbiphenyl | HCID 2734938 | — |
| Catalyst | HCID 178476681 | HCID 178476681 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 18.262% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 18.38% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-dc2139028835419a968215b7a73f3f39 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
