HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1340707Generated: October 31, 2026
3-Bromopyridine → 4-(4-Phenylpiperidin-1-yl)pyridine
https://huagongshe.com/reaction/1340707
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | Sodium t-butoxide | HCID 23676156 | — |
| Catalyst | Cuprous chloride | HCID 62652 | — |
| Catalyst | 1~4~,2~4~,3~4~-Tri-tert-butyl-1~2~,2~2~:2~6~,3~2~-terpyridine | HCID 4229824 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 17.079% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 17.387% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-3f74379597034b249fc4e3035e4dd405 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
