4-(2-Fluorophenyl)phenol → HCID 11191447, compound

HRID 13409Notes

Reaction equation

HRID 13409 reaction equation
[C:1]([N:4]1[CH2:8][CH2:7][CH:6]([F:9])[CH:5]1[C:10]1[C:15](F)=[CH:14][C:13]([NH:17][C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)=O)=[C:12]([N+:26]([O-])=O)[CH:11]=1)(=[O:3])[CH3:2].[F:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[C:36]1[CH:41]=[CH:40][C:39]([OH:42])=[CH:38][CH:37]=1>>[C:1]([N:4]1[CH2:8][CH2:7][CH:6]([F:9])[CH:5]1[C:10]1[C:15]([O:42][C:39]2[CH:38]=[CH:37][C:36]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=3[F:29])=[CH:41][CH:40]=2)=[CH:14][C:13]2[N:17]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[NH:26][C:12]=2[CH:11]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 3454194-(2-Fluorophenyl)phenolHCID 23145151N-(4-(1-acetyl-3-fluoropyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridin-2-carboxamide

Product 1

HCID 11191447HCID 11191447, compound

Procedure

The entitled compound was obtained in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using N-(4-(1-acetyl-3-fluoropyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridin-2-carboxamide enantiomer A and 2′-fluorobiphenyl-4-ol.

Workup

  1. customThe entitled compound was obtained in the same method as in Example 338 (step 5) or in accordance with the method

Sources & evidence

ORD record
ord-acdc3df757bc47a89ef49b81fdb00d19
Source dataset
uspto-grants-2010_06
Patent number
US07728025B2

Reaction notes

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