HRID13409

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID345419

4-(2-fluorophenyl)phenol

C12H9FO

结构：CC(=O)N1CCC(F)C1c1cc([N+](=O)[O-])c(NC(=O)c2ccccn2)cc1F

HCID23145151

未命名化合物

PRODUCTS

生成物

结构：CC(=O)N1CCC(F)C1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(-c2ccccc2F)cc1

HCID11191447

未命名化合物

PROCEDURE

实验过程

The entitled compound was obtained in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using N-(4-(1-acetyl-3-fluoropyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridin-2-carboxamide enantiomer A and 2′-fluorobiphenyl-4-ol.

WORKUP

后处理

customThe entitled compound was obtained in the same method as in Example 338 (step 5) or in accordance with the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-acdc3df757bc47a89ef49b81fdb00d19
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07728025B2
来源说明: uspto-grants-2010_06

反应 SMILES

[C:1]([N:4]1[CH2:8][CH2:7][CH:6]([F:9])[CH:5]1[C:10]1[C:15](F)=[CH:14][C:13]([NH:17][C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)=O)=[C:12]([N+:26]([O-])=O)[CH:11]=1)(=[O:3])[CH3:2].[F:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[C:36]1[CH:41]=[CH:40][C:39]([OH:42])=[CH:38][CH:37]=1>>[C:1]([N:4]1[CH2:8][CH2:7][CH:6]([F:9])[CH:5]1[C:10]1[C:15]([O:42][C:39]2[CH:38]=[CH:37][C:36]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=3[F:29])=[CH:41][CH:40]=2)=[CH:14][C:13]2[N:17]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=3)[NH:26][C:12]=2[CH:11]=1)(=[O:3])[CH3:2]