HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1341907Generated: November 2, 2026
3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine
https://huagongshe.com/reaction/1341907
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reagent | Sodium trimethylsilanolate | HCID 23672319 | — |
| Catalyst | 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl | HCID 11269872 | — |
| Catalyst | HCID 178428205 | HCID 178428205 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 4.608% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-3b09a10214ba4fbab5b6011d34a060f3 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
