2-Pyridinemethanamine → 2-[3-[(3,5-difluorophenyl)methyl]-4-methyl-2-oxoimidazolidin-1-yl]-4-methyl-N-(pyridin-2-ylmethyl)-1,3-thiazole-5-carboxamide
Reaction equation
[F:17][c:18]1[cH:19][cH:20][c:21]([CH2:22][N:23]2[CH:24]([CH3:25])[CH2:26][N:27]([c:28]3[s:29][c:30]([C:31]([OH:32])=[O:33])[c:34]([CH3:35])[n:36]3)[C:37]2=[O:38])[cH:39][cH:40]1.[F:41][c:42]1[cH:43][c:44]([CH2:45][N:46]2[C:47](=[O:61])[N:48]([c:52]3[s:53][c:54]([C:58](=[O:59])[OH:60])[c:55]([CH3:57])[n:56]3)[CH2:49][CH:50]2[CH3:51])[cH:62][c:63]([F:65])[cH:64]1.[n:1]1[cH:2][cH:3][cH:4][c:5]([CH2:6][NH2:7])[cH:8]1.[n:9]1[c:10]([CH2:15][NH2:16])[cH:11][cH:12][cH:13][cH:14]1>>[n:9]1[c:10]([CH2:15][NH:16][C:58]([c:54]2[s:53][c:52]([N:48]3[C:47](=[O:61])[N:46]([CH2:45][c:44]4[cH:43][c:42]([F:41])[cH:64][c:63]([F:65])[cH:62]4)[CH:50]([CH3:51])[CH2:49]3)[n:56][c:55]2[CH3:57])=[O:59])[cH:11][cH:12][cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6e6849536dce4561aa344d930bee7d81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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