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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1342330Generated: November 1, 2026

3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine

https://huagongshe.com/reaction/1342330

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant4-PhenylpiperidineHCID 69873—
ReagentCID 21226062HCID 21226062—
Catalyst4-{2-[Di(tricyclo[3.3.1.1~3,7~]decan-1-yl)phosphanyl]phenyl}morpholineHCID 46848051—
CatalystHCID 178461822HCID 178461822—
SolventDiglymeHCID 8150—
ProductCaffeineHCID 2519—
Product3-(4-Phenyl-1-piperidinyl)pyridineHCID 1223802230%
Product4-(4-Phenylpiperidin-1-yl)pyridineHCID 1398883370%

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1021/jacs.6c05959
Source datasetHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-38595fdd152f46c49ffa1962e4fc2d4d
Source noteHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions