Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1342876Generated: October 29, 2026

3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine

https://huagongshe.com/reaction/1342876

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant4-PhenylpiperidineHCID 69873—
ReagentCID 21226062HCID 21226062—
Catalyst2-((2,6-Dimethoxyphenyl)amino)-2-oxoacetic acidHCID 118864503—
CatalystHCID 178486303HCID 178486303—
SolventDiglymeHCID 8150—
ProductCaffeineHCID 2519—
Product3-(4-Phenyl-1-piperidinyl)pyridineHCID 1223802230%
Product4-(4-Phenylpiperidin-1-yl)pyridineHCID 1398883370%

Reaction Conditions

Temperature30 °C

Provenance & Evidence

DOI10.1021/jacs.6c05959
Source datasetHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-36822671678c497ebdf0692e2e66b217
Source noteHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions