N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamide → 4-(3,4-Difluorophenyl)-N-(3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}propyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([CH:9]2[C:10]([C:17](=[O:18])[OH:19])=[C:11]([CH3:16])[NH:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8].[NH2:20][CH2:21][CH2:22][CH2:23][N:24]1[CH2:25][CH2:26][CH:27]([c:30]2[cH:31][c:32]([NH:36][C:37]([CH:38]([CH3:39])[CH3:40])=[O:41])[cH:33][cH:34][cH:35]2)[CH2:28][CH2:29]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[C:10]([C:17](=[O:19])[NH:20][CH2:21][CH2:22][CH2:23][N:24]3[CH2:25][CH2:26][CH:27]([c:30]4[cH:31][c:32]([NH:36][C:37]([CH:38]([CH3:39])[CH3:40])=[O:41])[cH:33][cH:34][cH:35]4)[CH2:28][CH2:29]3)=[C:11]([CH3:16])[NH:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-612a500266f84c8e8c716255670939cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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