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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 134369Generated: October 25, 2026

Acetonitrile → 4-Difluoromethoxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

https://huagongshe.com/reaction/134369

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2,2-Difluoro-2-(fluorosulfonyl)acetic acidHCID 2737516—
Reactant1-(tert-Butyl) 2-methyl 4-(hydroxymethyl)pyrrolidine-1,2-dicarboxylateHCID 23595753—
Product4-Difluoromethoxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 66620438—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-9913c6a79b8e45bca8a93dfd3c128935
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)