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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 134399Generated: October 25, 2026

Tetrahydrofuran → 3-(4-Bromo-2-chloro-benzyl)-cis-1-(4-fluoro-cyclohexyl)-pyrrolidin-2-one

https://huagongshe.com/reaction/134399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
Reactant4-Bromo-1-(bromomethyl)-2-chlorobenzeneHCID 21914486—
Reactantcis-1-(4-Fluoro-cyclohexyl)-pyrrolidin-2-oneHCID 57878602—
Product3-(4-Bromo-2-chloro-benzyl)-cis-1-(4-fluoro-cyclohexyl)-pyrrolidin-2-oneHCID 57878597—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-c762524ac1154c59b2536a73e5a6ba8f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)