Methanol → 1-(2-(2-((5-ethoxy-2-fluoro-3-isopropoxyphenyl)(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)methyl)-1-trityl-1H-imidazol-4-yl)phenyl)ethanol
Reaction equation
[BH4-:62].[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([O:58][CH:59]([CH3:60])[CH3:61])[c:7]([F:57])[c:8]([CH:10]([c:11]2[n:12]([C:25]([c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:38]3[cH:39][cH:40][cH:41][cH:42][cH:43]3)[cH:13][c:14](-[c:16]3[c:17]([C:22]([CH3:23])=[O:24])[cH:18][cH:19][cH:20][cH:21]3)[n:15]2)[NH:44][c:45]2[cH:46][cH:47][c:48](-[c:51]3[n:52][o:53][c:54]([CH3:56])[n:55]3)[cH:49][cH:50]2)[cH:9]1.[CH3:64][OH:65].[Na+:63]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([O:58][CH:59]([CH3:60])[CH3:61])[c:7]([F:57])[c:8]([CH:10]([c:11]2[n:12]([C:25]([c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:38]3[cH:39][cH:40][cH:41][cH:42][cH:43]3)[cH:13][c:14](-[c:16]3[c:17]([CH:22]([CH3:23])[OH:24])[cH:18][cH:19][cH:20][cH:21]3)[n:15]2)[NH:44][c:45]2[cH:46][cH:47][c:48](-[c:51]3[n:52][o:53][c:54]([CH3:56])[n:55]3)[cH:49][cH:50]2)[cH:9]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f46401f786b44db28b9d229688c9b588
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…