HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1344147Generated: October 30, 2026
4-Phenylpiperidine → 4-(4-Phenylpiperidin-1-yl)pyridine
https://huagongshe.com/reaction/1344147
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 3-Iodopyridine | HCID 70714 | — |
| Reagent | Sodium t-butoxide | HCID 23676156 | — |
| Catalyst | 5-Methyl-2-(2,4,6-trimethylphenyl)-2H-imidazo[1,5-a]pyridin-4-ium chloride | HCID 16218372 | — |
| Catalyst | HCID 178427257 | HCID 178427257 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 0% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 21.451% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-4079e514b92a4a3a89b21b88b596d3f7 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
