Ethanol → tert-Butyl 4-(aminooxy)piperidine-1-carboxylate

HRID 134416Notes

Reaction equation

HRID 134416 reaction equation
[CH3:28][CH2:29][OH:30].[NH2:1][NH2:2].[O:3]=[C:4]1[N:5]([O:14][CH:15]2[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[C:12](=[O:13])[c:7]2[c:6]1[cH:11][cH:10][cH:9][cH:8]2>>[NH2:5][O:14][CH:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 702EthanolHCID 9321HydrazineHCID 21751544Tert-butyl 4-(1,3-dioxoisoindolin-2-yloxy)piperidine-1-carboxylate

Product 1

HCID 24729482tert-Butyl 4-(aminooxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-b4bb0c37168b42ea8907749cb7116ad4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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