6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acid → 6-(cyclopropylmethoxy)-N-[2-cyclopropyl-1-(1,3-thiazol-2-yl)ethyl]-5-(oxan-4-yl)pyridine-2-carboxamide
Reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([CH:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[CH:21]1([CH2:24][CH:25]([c:26]2[s:27][cH:28][cH:29][n:30]2)[NH2:31])[CH2:22][CH2:23]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([CH:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:31][CH:25]([CH2:24][CH:21]3[CH2:22][CH2:23]3)[c:26]3[s:27][cH:28][cH:29][n:30]3)[n:11]2)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-d3b1cfff7e0346d8a2abdb81cccd707b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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