Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1346310Generated: October 28, 2026

4-Phenylpiperidine → 3-(4-Phenyl-1-piperidinyl)pyridine

https://huagongshe.com/reaction/1346310

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PhenylpiperidineHCID 69873—
Reactant3-IodopyridineHCID 70714—
ReagentCID 21226062HCID 21226062—
Catalyst2,2,6,6-Tetramethyl-3,5-heptanedioneHCID 70700—
Catalystpalladium(II) acetateHCID 167845—
SolventDimethyl SulfoxideHCID 679—
ProductCaffeineHCID 2519—
Product3-(4-Phenyl-1-piperidinyl)pyridineHCID 1223802230%
Product4-(4-Phenylpiperidin-1-yl)pyridineHCID 1398883370%

Reaction Conditions

Temperature30 °C

Provenance & Evidence

DOI10.1021/jacs.6c05959
Source datasetHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-18bd5f5745bf455caa2c72da52076a9f
Source noteHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions