HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1346331Generated: October 28, 2026
4-Phenylpiperidine → 4-(4-Phenylpiperidin-1-yl)pyridine
https://huagongshe.com/reaction/1346331
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 3-Iodopyridine | HCID 70714 | — |
| Reagent | Sodium t-butoxide | HCID 23676156 | — |
| Catalyst | copper(I) bromide | HCID 24593 | — |
| Catalyst | N,N'-dibenzylethanediamide | HCID 219253 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 0% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 19.808% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-025870afdd3c4ce3b9a4c27dc6cf410b |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
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