HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1346612Generated: November 2, 2026
4-Phenylpiperidine → 3-(4-Phenyl-1-piperidinyl)pyridine
https://huagongshe.com/reaction/1346612
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 3-Iodopyridine | HCID 70714 | — |
| Reagent | Sodium trimethylsilanolate | HCID 23672319 | — |
| Catalyst | 1-(5,6,7,8-Tetrahydroquinolin-8-yl)ethan-1-one | HCID 42604452 | — |
| Catalyst | HCID 178427257 | HCID 178427257 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 1.039% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-7d04e148c41149b2992d2c40420546a5 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
