HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1346940Generated: October 30, 2026
4-Phenylpiperidine → 3-(4-Phenyl-1-piperidinyl)pyridine
https://huagongshe.com/reaction/1346940
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 3-Iodopyridine | HCID 70714 | — |
| Reagent | Sodium trimethylsilanolate | HCID 23672319 | — |
| Catalyst | copper(I) bromide | HCID 24593 | — |
| Catalyst | (R)-N,Nμ-Dimethyl-2,2μ-diamino-1,1μ-binaphthyl, (R)-N,Nμ-Dimethyl-1,1μ-binaphthalene-2,2μ-diamine | HCID 628556 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Caffeine | HCID 2519 | — |
| Product | 3-(4-Phenyl-1-piperidinyl)pyridine | HCID 122380223 | 0% |
| Product | 4-(4-Phenylpiperidin-1-yl)pyridine | HCID 139888337 | 0% |
Provenance & Evidence
| DOI | 10.1021/jacs.6c05959 |
|---|
| Source dataset | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
| ORD ID | ord-a83adb0ab83b4a6fa8f720ea02e36c52 |
|---|
| Source note | High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions |
|---|
