2-(4-Cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester → (+)-2-(4-Aminomethyl-3-fluoro-phenoxy)-propionic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[O:9][c:10]1[cH:11][c:12]([F:18])[c:13]([C:16]#[N:17])[cH:14][cH:15]1)=[O:19].[C:20]([O:21][C:22](=[O:23])[CH:24]([O:25][c:26]1[cH:27][cH:28][c:29]([C:30]#[N:31])[c:32]([F:33])[cH:34]1)[CH3:35])([CH3:36])([CH3:37])[CH3:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([CH3:8])[O:9][c:10]1[cH:11][c:12]([F:18])[c:13]([CH2:16][NH2:17])[cH:14][cH:15]1)=[O:19]Participants
2
Sources & evidence
- ORD record
- ord-53bfb950e63a47268b6b817b0b15a94e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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