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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13479Generated: October 25, 2026

1-Ethyl-4-(4-nitrophenyl)piperazine → 4-(4-Ethylpiperazin-1-yl)aniline

https://huagongshe.com/reaction/13479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-4-(4-nitrophenyl)piperazineHCID 2857549—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product4-(4-Ethylpiperazin-1-yl)anilineHCID 936738—

Reaction Steps

The mixture containing 4-ethyl-1-(4-nitrophenyl)piperazine in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield 4-(4-ethylpiperazinyl)phenylamine. MS: MH+=205.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728010B2
Source datasetuspto-grants-2010_06
ORD IDord-7dc8a99f75a74d88b13febfbb563aee0
Source noteuspto-grants-2010_06