Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1348095Generated: October 30, 2026

3-Bromopyridine → 3-(4-Phenyl-1-piperidinyl)pyridine

https://huagongshe.com/reaction/1348095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant4-PhenylpiperidineHCID 69873—
ReagentPotassium tert-butoxideHCID 23665647—
CatalystHCID 178476681HCID 178476681—
SolventDimethyl SulfoxideHCID 679—
ProductCaffeineHCID 2519—
Product3-(4-Phenyl-1-piperidinyl)pyridineHCID 12238022310.935%
Product4-(4-Phenylpiperidin-1-yl)pyridineHCID 13988833710.763%

Reaction Conditions

Temperature30 °C

Provenance & Evidence

DOI10.1021/jacs.6c05959
Source datasetHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-7983fda63f0e4af1b0ebd6a76996a6b1
Source noteHigh-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions