2-Methylpiperidine → HCID 23018279, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.63 g of 5,7-dichloro-6-(2,4,6-trifluorophenyl)-imidazo[1,2-a]pyrimidine, 0.79 g of 2-methylpiperidine and 2 ml of chloroform was heated at 80° C. for one hour. The reaction mixture was allowed to cool and subjected to silica gel column chromatography to give 0.30 g of 5-(2-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)-7-chloroimidazo[1,2-a]pyrimidine.

Provenance & Evidence