p-Fluoronitrobenzene → Ethyl-[1-(4-nitro-phenyl)-pyrrolidin-3-yl]-amine

HRID 1348570Notes

Reaction equation

[CH2:1]([NH:3][CH:4]1[CH2:8][CH2:7][NH:6][CH2:5]1)[CH3:2].F[C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=1>>[CH2:1]([NH:3][CH:4]1[CH2:8][CH2:7][N:6]([C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=2)[CH2:5]1)[CH3:2]

Participants

Reactant 2

HCID 9590p-Fluoronitrobenzene

HCID 142809003-(Ethylamino)pyrrolidine

Product 1

HCID 21091592Ethyl-[1-(4-nitro-phenyl)-pyrrolidin-3-yl]-amine

Procedure

The compound was prepared from 3-ethylamino-pyrolidine (TCI-US) and 4-fluoro-nitrobenzene (Aldrich) following the procedure used in Example 1. MS (m+H)+: 236.

Sources & evidence

ORD record: ord-69fb25d19ffc4a788494bd4997b090f4
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07211576B2

Reaction notes

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