Ethanol → (RS)-1-cyclopropyl-7-fluoro-8-[3-(4-methoxyphenyl)-1-piperazinyl]-4-oxo-1,4-dihydrobenzo [b][1,8]naphthyridine-3-carboxylic acid

HRID 134863Notes

Reaction equation

HRID 134863 reaction equation
[CH3:41][CH2:42][OH:43].[CH:1]1([n:4]2[cH:5][c:6]([C:34](=[O:35])[O:36][CH2:37][CH3:38])[c:7](=[O:33])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[cH:14][c:15]([N:19]2[CH2:20][CH:21]([c:25]3[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]3)[NH:22][CH2:23][CH2:24]2)[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1.[K+:40].[OH-:39]>>[CH:1]1([n:4]2[cH:5][c:6]([C:34](=[O:35])[OH:36])[c:7](=[O:33])[c:8]3[cH:9][c:10]4[c:11]([n:12][c:13]23)[cH:14][c:15]([N:19]2[CH2:20][CH:21]([c:25]3[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]3)[NH:22][CH2:23][CH2:24]2)[c:16]([F:18])[cH:17]4)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 702EthanolHCID 813Potassium CationHCID 961HydroxideHCID 54470582HCID 54470582, compound

Product 1

HCID 53972680(RS)-1-cyclopropyl-7-fluoro-8-[3-(4-methoxyphenyl)-1-piperazinyl]-4-oxo-1,4-dihydrobenzo [b][1,8]naphthyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-680e1cce7a71478faf76db66ab676d85
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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