HCID 21091457, compound → HCID 21091461, compound

HRID 1348632Notes

Reaction equation

HRID 1348632 reaction equation
[CH:1]1([C@H:4]2[C@@H:10]([N:11](CC3C=CC=CC=3)CC3C=CC=CC=3)[C:9](=[O:26])[NH:8][C:7]3[CH:27]=[C:28]([F:31])[CH:29]=[CH:30][C:6]=3[O:5]2)[CH2:3][CH2:2]1>CO.[Pd]>[NH2:11][C@H:10]1[C:9](=[O:26])[NH:8][C:7]2[CH:27]=[C:28]([F:31])[CH:29]=[CH:30][C:6]=2[O:5][C@H:4]1[CH:1]1[CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 21091457HCID 21091457, compound

Product 1

HCID 21091461HCID 21091461, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The title compound was prepared by hydrogenation of (+)-(6S,7R)-6-cyclopropyl-7-dibenzylamino-2-fluoro-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one in methanol with Pd/C (10%), MS m/e (%): 235.1 (M−H, 100).

Sources & evidence

ORD record
ord-d7e3df0be35346eabb3a35378304906d
Source dataset
uspto-grants-2007_05
Patent number
US07211573B2

Reaction notes

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