Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | 2-Amino-5-methylphenol | HCID 76082 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15183276 | HCID 15183276 | — |
Reaction Steps
Pyridine (810 μl) and then, a little at a time, p-toluenesulfonyl chloride (1.91 g, 10 mmol) are added to a solution of 2-amino-5-methylphenol (1.23 g, 10 mmol) in CH2Cl2 (20 ml). The reaction mixture is stirred at 40° C. for 4 h. The solvent is distilled off under reduced pressure, ethyl acetate is added to the residue and the solid is filtered off with suction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07211592B2 |
|---|
| Source dataset | uspto-grants-2007_05 |
|---|
| ORD ID | ord-264c57f220ff499f8b10a9b293ca6b8c |
|---|
| Source note | uspto-grants-2007_05 |
|---|
