Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(2-hydroxyethyl)aminomethyl-2H-pyridazin-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-meth anesulfonyloxymethyl-2H-pyridazin-3-one | HCID 21991618 | — |
| 생성물 | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(2-hydroxyethyl)aminomethyl-2H-pyridazin-3-one | HCID 21991705 | 72.1% |
반응 단계
Following the procedure of Example 9(4), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and 2-aminoethanol were reacted to yield the title compound as a yellow oil (yield: 72.1%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07211577B2 |
| 출처 데이터셋 | uspto-grants-2007_05 |
| ORD ID | ord-f6656dac97624e1caf27c50236c0890c |
| 출처 메모 | uspto-grants-2007_05 |