tert-Butyl piperazine-1-carboxylate → HCID 21991632, compound

HRID 1348721Notes

Reaction equation

HRID 1348721 reaction equation
[CH2:1]([N:5]1[C:10](=[O:11])[C:9]([CH2:12]OS(C)(=O)=O)=[CH:8][C:7]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)=[N:6]1)[CH:2]([CH3:4])[CH3:3].[N:28]1([C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[C:37]([O:36][C:34]([N:28]1[CH2:33][CH2:32][N:31]([CH2:12][C:9]2[C:10](=[O:11])[N:5]([CH2:1][CH:2]([CH3:3])[CH3:4])[N:6]=[C:7]([C:18]3[CH:19]=[CH:20][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:22][CH:23]=3)[CH:8]=2)[CH2:30][CH2:29]1)=[O:35])([CH3:40])([CH3:39])[CH3:38]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 219915502-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromet hylphenyl)-2H-pyridazin-3-one

Product 1

HCID 21991632HCID 21991632, compoundYield 83.5%

Procedure

Following the procedure of Example 1(10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromethyl phenyl)-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 83.5%).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-f6bd04f2e98d499786058e6e03cb42ed
Source dataset
uspto-grants-2007_05
Patent number
US07211577B2

Reaction notes

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