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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1348749Generated: October 29, 2026

1-Methylpiperazine → 2-cyclopropylmethyl-4-(4-methyl-1-piperazinyl)methyl-6-[4-(methylsulfinyl)phenyl]-2H-pyridazin-3-one

https://huagongshe.com/reaction/1348749

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 23018243HCID 23018243—
Product2-cyclopropylmethyl-4-(4-methyl-1-piperazinyl)methyl-6-[4-(methylsulfinyl)phenyl]-2H-pyridazin-3-oneHCID 2199140460.6%

Reaction Steps

Following the procedure of Example 1(10), 2-cyclopropylmethyl-4-methanesulfonyloxymethyl-6-[4-(methyl-sulfinyl)phenyl]-2H-pyridazin-3-one and 1-methylpiperazine were reacted to yield the title compound as a yellow oil (yield: 60.6%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211577B2
Source datasetuspto-grants-2007_05
ORD IDord-9d58cb96313d4d0a8d182c5712ea0b93
Source noteuspto-grants-2007_05