tert-Butyl piperazine-1-carboxylate → HCID 22562286, compound

HRID 1348797Notes

Reaction equation

HRID 1348797 reaction equation
[Cl:1][C:2]1[CH:29]=[CH:28][CH:27]=[C:26]([Cl:30])[C:3]=1[CH2:4][N:5]1[C:10](=[O:11])[C:9]([CH2:12]OS(C)(=O)=O)=[CH:8][C:7]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[C:20]([CH3:25])[CH:19]=2)=[N:6]1.[N:31]1([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[C:40]([O:39][C:37]([N:31]1[CH2:36][CH2:35][N:34]([CH2:12][C:9]2[C:10](=[O:11])[N:5]([CH2:4][C:3]3[C:26]([Cl:30])=[CH:27][CH:28]=[CH:29][C:2]=3[Cl:1])[N:6]=[C:7]([C:18]3[CH:23]=[CH:22][C:21]([F:24])=[C:20]([CH3:25])[CH:19]=3)[CH:8]=2)[CH2:33][CH2:32]1)=[O:38])([CH3:43])([CH3:42])[CH3:41]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 22562232HCID 22562232, compound

Product 1

HCID 22562286HCID 22562286, compoundYield 90.8%

Procedure

Following the procedure of Example 1(10), 2-(2,6-dichlorobenzyl)-6-(4-fluoro-3-methylphenyl)-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 90.8%).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-b12546f6990542cbaaa124e935df5553
Source dataset
uspto-grants-2007_05
Patent number
US07211577B2

Reaction notes

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