Potassium Carbonate → HCID 17965967, compound

Participants

Reaction Steps

A solution of Example 36C (230 mg, 1.0 mmol) in DMF (1.5 mL) at 0° C. was treated with PBr3 (114 mL, 1.2 mmol) and lithium bromide (104 mg, 1.2 mmol), stirred for 3 hours, treated with water, adjusted to pH>7 with K2CO3, and extracted with dichloromethane. The combined extracts were dried (MgSO4), filtered, and concentrated to provide the desired product of sufficient purity for subsequent use.

Provenance & Evidence