Methanesulfonyl chloride → HCID 10160626, compound

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Reaction Steps

The material from step 3 of Example 24 (1 g, 0.0027 mol) was combined with methane sulfonyl chloride (345 mg, 0.003 mol) in 10 mL pyridine. The mixture was stirred at room temperature, under argon, for 3 hours. The reaction was then concentrated in vacuo. The resulting solid was washed with water and diethyl ether, and was then air dried to give the desired as a tan solid. 950 mg. (MW=443.46, 79% yield). LC/MS m/z=444 (m+1).

Provenance & Evidence