5-Phenyl-1,3,4-thiadiazole-2-sulfonyl chloride → HCID 21092810, compound

HRID 1348961Notes

Reaction equation

HRID 1348961 reaction equation
Cl.Cl.[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[CH3:4].[C:13]1([C:19]2[S:23][C:22]([S:24](Cl)(=[O:26])=[O:25])=[N:21][N:20]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH:11][S:24]([C:22]1[S:23][C:19]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:20][N:21]=1)(=[O:25])=[O:26])[CH3:4]

Participants

3

Reactant 2

HCID 210927565-Phenyl-1,3,4-thiadiazole-2-sulfonyl chlorideHCID 74889816N-beta-Aminoethyl-gly-oet 2hcl

Product 1

HCID 21092810HCID 21092810, compound

Procedure

The title compound was synthesized by the reaction of N-(2-aminoethyl)-glycine ethyl ester 2HCl with 5-phenyl-1,3,4-thiadiazole-2-sulfonyl chloride as per the procedure of example 1. 1H NMR (500 MHz; DMSO-d6) δ 8.05 (d, 2H), 7.60–7.56 (m, 3H), 4.02 (q, 2H), 3.26 (s, 2H), 3.16 (t, 2H), 2.64 (t, 2H), 1.14 (t, 3H).

Sources & evidence

ORD record
ord-dfa17209581b4f699ab23fa904f04f9b
Source dataset
uspto-grants-2007_05
Patent number
US07211668B2

Reaction notes

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