5-(2,5-Dichlorophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride → HCID 21092765, compound

HRID 1348962Notes

Reaction equation

HRID 1348962 reaction equation
Cl.Cl.[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[CH3:4].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:15]=1[C:21]1[S:25][C:24]([S:26](Cl)(=[O:28])=[O:27])=[N:23][N:22]=1>>[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH:11][S:26]([C:24]1[S:25][C:21]([C:15]2[CH:16]=[C:17]([Cl:20])[CH:18]=[CH:19][C:14]=2[Cl:13])=[N:22][N:23]=1)(=[O:28])=[O:27])[CH3:4]

Participants

3

Reactant 2

HCID 210927485-(2,5-Dichlorophenyl)-1,3,4-thiadiazole-2-sulfonyl chlorideHCID 74889816N-beta-Aminoethyl-gly-oet 2hcl

Product 1

HCID 21092765HCID 21092765, compound

Procedure

The title compound was synthesized by the reaction of N-(2-aminoethyl)-glycine ethyl ester 2HCl with 5-(2,5-Dichlorophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride as per the procedure of example 1. 1H NMR (500 MHz; DMSO-d6) δ 8.27 (s, 1H), 7.80 (d, 1H), 7.75 (d, 1H), 4.03 (q, 2H), 3.35 (s, 2H), 3.21 (t, 2H), 2.71 (t, 2H), 1.15 (t, 3H).

Sources & evidence

ORD record
ord-abbe78122b4c4a32a77b321b19985736
Source dataset
uspto-grants-2007_05
Patent number
US07211668B2

Reaction notes

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