5-(2-Nitrophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride → HCID 21092771, compound

HRID 1348964Notes

Reaction equation

HRID 1348964 reaction equation
Cl.Cl.[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[CH3:4].[N+:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[C:22]1[S:26][C:25]([S:27](Cl)(=[O:29])=[O:28])=[N:24][N:23]=1)([O-:15])=[O:14]>>[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH:11][S:27]([C:25]1[S:26][C:22]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N+:13]([O-:15])=[O:14])=[N:23][N:24]=1)(=[O:28])=[O:29])[CH3:4]

Participants

3

Reactant 2

HCID 210927505-(2-Nitrophenyl)-1,3,4-thiadiazole-2-sulfonyl chlorideHCID 74889816N-beta-Aminoethyl-gly-oet 2hcl

Product 1

HCID 21092771HCID 21092771, compound

Procedure

The title compound was synthesized by the reaction of N-(2-aminoethyl)-glycine ethyl ester 2HCl with 5-(2-nitrophenyl)-1,3,4-thiadiazole-2-sulfonyl chloride as per the procedure of example 1. 1H NMR (MHz; DMSO-d6) δ 8.16 (d, 1H), 7.81–7.78 (m, 3H), 4.02 (q, 2H), 3.34 (s, 2H), 3.21 (t, 2H), 2.70 (t, 2H), 1.15 (t, 3H).

Sources & evidence

ORD record
ord-25fe04c8be07421f85bddf1667075b5e
Source dataset
uspto-grants-2007_05
Patent number
US07211668B2

Reaction notes

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