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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1348975Generated: October 25, 2026

2-(5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic acid → N-{2-[5-(4-Nitrophenyl)-1,3,4-thiadiazole-2-sulfonylamino]-ethyl}-N-[(thymin-1-yl)-acetyl]-glycine Ethyl Ester

https://huagongshe.com/reaction/1348975

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic acidHCID 853753—
ReactantN-{2-[5-(4-nitrophenyl)-1,3,4-thiadiazole-2-sulfonylamino]-ethyl}-glycine ethyl esterHCID 21092799—
ProductN-{2-[5-(4-Nitrophenyl)-1,3,4-thiadiazole-2-sulfonylamino]-ethyl}-N-[(thymin-1-yl)-acetyl]-glycine Ethyl EsterHCID 21092801—

Reaction Steps

The title compound was synthesized by the reaction of N-{2-[5-(4-nitrophenyl)-1,3,4-thiadiazole-2-sulfonylamino]-ethyl}-glycine ethyl ester with (thymin-1-yl)-acetic acid as per the procedure of example 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211668B2
Source datasetuspto-grants-2007_05
ORD IDord-9846e4862e7f4bf6889d6a82cd40a0cc
Source noteuspto-grants-2007_05