2-(5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic acid → HCID 21092739, compound

HRID 1348991Notes

Reaction equation

HRID 1348991 reaction equation
FC(F)(F)C(O)=[O:4].[CH3:8][C:9]1[S:13][C:12]([S:14]([N:17]2[CH2:22][CH2:21][NH:20][C:19](=O)[CH2:18]2)(=[O:16])=[O:15])=[N:11][N:10]=1.[N:24]1([CH2:33][C:34](O)=[O:35])[CH:32]=[C:30]([CH3:31])[C:28](=[O:29])[NH:27][C:25]1=[O:26]>>[CH3:8][C:9]1[S:13][C:12]([S:14]([N:17]2[CH2:22][CH2:21][N:20]([C:34](=[O:35])[CH2:33][N:24]3[CH:32]=[C:30]([CH3:31])[C:28](=[O:29])[NH:27][C:25]3=[O:26])[CH2:19][C:18]2=[O:4])(=[O:16])=[O:15])=[N:11][N:10]=1

Participants

3

Reactant 2

HCID 8537532-(5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic acidHCID 69034958HCID 69034958, compound

Product 1

HCID 21092739HCID 21092739, compound

Procedure

The title compound was synthesized by the reaction of 4-(5-methyl-1,3,4-thiadiazole-2-sulfonyl)-piperazin-2-one trifluoroacetic acid salt with (thymin-1-yl)-acetic acid as per the procedure of method B described in example 64,

Sources & evidence

ORD record
ord-8d6264c3e12c4f609b9948b19096b614
Source dataset
uspto-grants-2007_05
Patent number
US07211668B2

Reaction notes

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