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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 134902Generated: October 26, 2026

Water → Ethyl 5-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-3-methyl-1-(2-pyrrolidin-1-yl-ethyl)-1h-indole-2-carboxylate

https://huagongshe.com/reaction/134902

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantPiperidineHCID 8082—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant5-(4-Chlorophenyl)-2-iodopyridineHCID 85969849—
Reactantethyl 5-ethynyl-3-methyl-1-(2-pyrrolidin-1-yl-ethyl)-1H-indole-2-carboxylateHCID 86594685—
ProductEthyl 5-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-3-methyl-1-(2-pyrrolidin-1-yl-ethyl)-1h-indole-2-carboxylateHCID 59835807—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-bb6cad4d5e94492cb46de9c8e022d8be
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)