HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → (2S,4EZ)-4-(tert-butoxyimino)-N-(2-methoxyethyl)-1-(2-oxo-6-pentyl-2H-pyran-3-yl)carbonyl-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride | HCID 22223512 | — |
| Reactant | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid | HCID 131725425 | — |
| Product | (2S,4EZ)-4-(tert-butoxyimino)-N-(2-methoxyethyl)-1-(2-oxo-6-pentyl-2H-pyran-3-yl)carbonyl-2-pyrrolidinecarboxamide | HCID 131725428 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid, 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride, and 2-methoxyethylamine the title compound was obtained in 75% purity by LC/MS. MS(ESI+): m/z=450.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211601B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-6450d76f17984a84a8a3542aa04d0afa |
| Source note | uspto-grants-2007_05 |