HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-9-ethylcarbazole → (2S)-1-[4-(dimethylamino)butanoyl]-N-(9-ethyl-9H-carbazol-3-yl)-4-methylene-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-9-ethylcarbazole | HCID 8588 | — |
| Reactant | 4-(Dimethylamino)butanoyl chloride | HCID 15087690 | — |
| Reactant | (2S)-1-((tert-butoxy)carbonyl)-4-methylidenepyrrolidine-2-carboxylic acid | HCID 21727417 | — |
| Product | (2S)-1-[4-(dimethylamino)butanoyl]-N-(9-ethyl-9H-carbazol-3-yl)-4-methylene-2-pyrrolidinecarboxamide | HCID 69249213 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-methyleneproline, 4-(dimethylamino)butanoyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 51% purity by LC/MS. MS(ESI+): m/z=433.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211601B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-658d88c6dab04d5cac069acf6fd58a71 |
| Source note | uspto-grants-2007_05 |