HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Aminoquinoline → (2S,4EZ)-4-{[(3,4-dichlorobenzyl)oxy]imino}-1-[4-(dimethylamino)butanoyl]-N-(6-quinolinyl)-2-pyrrolidinecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Aminoquinoline | HCID 11373 | — |
| Edukt | 4-(Dimethylamino)butanoyl chloride | HCID 15087690 | — |
| Edukt | (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(3,4-dichlorobenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid | HCID 131725417 | — |
| Produkt | (2S,4EZ)-4-{[(3,4-dichlorobenzyl)oxy]imino}-1-[4-(dimethylamino)butanoyl]-N-(6-quinolinyl)-2-pyrrolidinecarboxamide | HCID 131725461 | — |
Reaktionsschritte
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(3,4-dichlorobenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid, 4-(dimethylamino)butanoyl chloride, and 6-quinolinamine the title compound was obtained in 95% purity by LC/MS. MS(ESI+): m/z=542.6.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07211601B2 |
| Quelldatensatz | uspto-grants-2007_05 |
| ORD ID | ord-e91d1b38f5db43e09ab478a5f8a8e882 |
| Quellennotiz | uspto-grants-2007_05 |