3-Amino-9-ethylcarbazole → HCID 69249813, compound

HRID 1349113Notes

Reaction equation

HRID 1349113 reaction equation
C(OC([N:8]1[CH2:12][C:11](=[CH:13][Cl:14])[CH2:10][C@H:9]1[C:15]([OH:17])=O)=O)(C)(C)C.[CH2:18]([N:20]1[C:32]2[CH:31]=[CH:30][C:29]([NH2:33])=[CH:28][C:27]=2[C:26]2[C:21]1=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH3:19]>>[Cl:14][CH:13]=[C:11]1[CH2:12][NH:8][C@H:9]([C:15]([NH:33][C:29]2[CH:30]=[CH:31][C:32]3[N:20]([CH2:18][CH3:19])[C:21]4[C:26]([C:27]=3[CH:28]=2)=[CH:25][CH:24]=[CH:23][CH:22]=4)=[O:17])[CH2:10]1

Participants

3

Reactant 2

HCID 85883-Amino-9-ethylcarbazoleHCID 69251379HCID 69251379, compound

Product 1

HCID 69249813HCID 69249813, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(chloromethylene)-2-pyrrolidinecarboxylic acid, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 73% purity by LC/MS. MS(ESI+): m/z=354.4.

Sources & evidence

ORD record
ord-4c05edeea1a14e2c8304a2464d242dd6
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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