HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Diethylethylenediamine → (2S,4EZ)-4-(tert-butoxyimino)-N-[2-(diethylamino)ethyl]-1-(diphenylacetyl)-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Diethylethylenediamine | HCID 60993 | — |
| Reactant | 2,2-Diphenylacetyl chloride | HCID 74637 | — |
| Reactant | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid | HCID 131725425 | — |
| Product | (2S,4EZ)-4-(tert-butoxyimino)-N-[2-(diethylamino)ethyl]-1-(diphenylacetyl)-2-pyrrolidinecarboxamide | HCID 131725482 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid, diphenylacetyl chloride, and N1,N1-diethyl-1,2-ethanediamine the title compound was obtained in 80% purity by LC/MS. MS(ESI+): m/z=493.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211601B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-291313e7c4704223b50cd0949f4600d0 |
| Source note | uspto-grants-2007_05 |