3-Amino-9-ethylcarbazole → HCID 131725494, compound

HRID 1349139Notes

Reaction equation

HRID 1349139 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][CH3:16])[CH2:10][C@H:9]1[C:17]([OH:19])=O)=[O:7])(C)(C)C.[CH3:20][O:21][CH2:22]C(Cl)=O.[CH2:26]([N:28]1[C:40]2[CH:39]=[CH:38][C:37]([NH2:41])=[CH:36][C:35]=2[C:34]2[C:29]1=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH3:27]>>[CH2:15]([O:14][N:13]=[C:11]1[CH2:12][N:8]([C:6](=[O:7])[CH2:22][O:21][CH3:20])[C@H:9]([C:17]([NH:41][C:37]2[CH:38]=[CH:39][C:40]3[N:28]([CH2:26][CH3:27])[C:29]4[C:34]([C:35]=3[CH:36]=2)=[CH:33][CH:32]=[CH:31][CH:30]=4)=[O:19])[CH2:10]1)[CH3:16]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 96623Methoxyacetyl chlorideHCID 58714540(2S,4EZ)-1-(tertbutoxycarbonyl)-4-(ethoxyirnino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725494HCID 131725494, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, methoxyacetyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 88% purity by LC/MS. MS(ESI+): m/z=437.2.

Sources & evidence

ORD record
ord-d17d250526ca43ecb11e54d3779033e2
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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