3-Amino-9-ethylcarbazole → HCID 131725506, compound

HRID 1349150Notes

Reaction equation

HRID 1349150 reaction equation
[CH2:1]([O:4][N:5]=[C:6]1[CH2:10][N:9]([C:11]([O:13]C(C)(C)C)=O)[C@H:8]([C:18]([OH:20])=O)[CH2:7]1)[CH:2]=[CH2:3].[O:21]([C:28]1[CH:36]=[CH:35][C:31](C(Cl)=O)=[CH:30][CH:29]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.[CH2:37]([N:39]1[C:51]2[CH:50]=[CH:49][C:48]([NH2:52])=[CH:47][C:46]=2[C:45]2[C:40]1=[CH:41][CH:42]=[CH:43][CH:44]=2)[CH3:38]>>[CH2:1]([O:4][N:5]=[C:6]1[CH2:10][N:9]([C:11](=[O:13])[C:31]2[CH:30]=[CH:29][C:28]([O:21][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)=[CH:36][CH:35]=2)[C@H:8]([C:18]([NH:52][C:48]2[CH:49]=[CH:50][C:51]3[N:39]([CH2:37][CH3:38])[C:40]4[C:45]([C:46]=3[CH:47]=2)=[CH:44][CH:43]=[CH:42][CH:41]=4)=[O:20])[CH2:7]1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 741934-Phenoxybenzoyl chlorideHCID 58714562(2S,4EZ)-4-[(allyloxy)imino)-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725506HCID 131725506, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-4-[(allyloxy)-imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, 4-phenoxybenzoyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 63% purity by LC/MS. MS(ESI+): m/z=573.4.

Sources & evidence

ORD record
ord-7b5b73fdebb14496b57acdc3ba53df21
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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