Acetyl chloride → HCID 131725511, compound

HRID 1349155Notes

Reaction equation

HRID 1349155 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.[C:19](Cl)(=O)C.[CH2:23]([N:25]1[C:37]2[CH:36]=[CH:35][C:34]([NH2:38])=[CH:33][C:32]=2[C:31]2[C:26]1=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH3:24]>>[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([NH:38][C:34]1[CH:35]=[CH:36][C:37]2[N:25]([CH2:23][CH3:24])[C:26]3[C:31]([C:32]=2[CH:33]=1)=[CH:30][CH:29]=[CH:28][CH:27]=3)=[O:18])(=[O:7])[CH3:19]

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 85883-Amino-9-ethylcarbazoleHCID 58714586(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725511HCID 131725511, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, acetyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 69% purity by LC/MS. MS(ESI+): m/z=393.2.

Sources & evidence

ORD record
ord-2b76865841ee4136933bd2b37f3aed0c
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

Loading…