3-Amino-9-ethylcarbazole → HCID 131725519, compound

HRID 1349164Notes

Reaction equation

HRID 1349164 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.[CH3:19][N:20]([CH3:27])[CH2:21][CH2:22][CH2:23]C(Cl)=O.[CH2:28]([N:30]1[C:42]2[CH:41]=[CH:40][C:39]([NH2:43])=[CH:38][C:37]=2[C:36]2[C:31]1=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH3:29]>>[CH3:19][N:20]([CH3:27])[CH2:21][CH2:22][CH2:23][C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([NH:43][C:39]1[CH:40]=[CH:41][C:42]2[N:30]([CH2:28][CH3:29])[C:31]3[C:36]([C:37]=2[CH:38]=1)=[CH:35][CH:34]=[CH:33][CH:32]=3)=[O:18])=[O:7]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 150876904-(Dimethylamino)butanoyl chlorideHCID 58714586(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725519HCID 131725519, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 4-(dimethylamino)-butanoyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 42% purity by LC/MS. MS(ESI+): m/z=464.2.

Sources & evidence

ORD record
ord-67ce17d50c1c490abd93b1b5205e524c
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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