3-Amino-9-ethylcarbazole → HCID 69249993, compound

HRID 1349167Notes

Reaction equation

HRID 1349167 reaction equation
C(O[C:6]([N:8]1[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]1[C:10]([OH:12])=O)=[O:7])(C)(C)C.[O:17]=[C:18]1[C:23](C(Cl)=O)=[CH:22][CH:21]=[C:20]([CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[O:19]1.[CH2:32]([N:34]1[C:46]2[CH:45]=[CH:44][C:43]([NH2:47])=[CH:42][C:41]=2[C:40]2[C:35]1=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH3:33]>>[CH2:32]([N:34]1[C:46]2[CH:45]=[CH:44][C:43]([NH:47][C:10]([C@@H:9]3[CH2:13][C:14](=[CH2:16])[CH2:15][N:8]3[C:6]([C:23]3[C:18](=[O:17])[O:19][C:20]([CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:21][CH:22]=3)=[O:7])=[O:12])=[CH:42][C:41]=2[C:40]2[C:35]1=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH3:33]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 21727417(2S)-1-((tert-butoxy)carbonyl)-4-methylidenepyrrolidine-2-carboxylic acidHCID 222235122-oxo-6-pentyl-2H-pyran-3-carbonyl chloride

Product 1

HCID 69249993HCID 69249993, compound

Procedure

Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-methyleneproline, 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 70% purity by LC/MS. MS(ESI+): m/z=512.4.

Sources & evidence

ORD record
ord-4dc79af3a09540f9bda2c1b5c792cbda
Source dataset
uspto-grants-2007_05
Patent number
US07211601B2

Reaction notes

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